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There are two possible drug interactions. Neurontin (Gabapentin) has no direct drug interactions with the other three. There is a minor interaction between risperidone (Risperdal) and Topamax (Topiramate). There may be an increase in the risk of drowsiness, increased blood pressure or heart rate, loss of coordination, restlessness, sweating, vomiting, or other side effects. Natural antibiotics, conversely, work with the body'S natural powers to rid it of infection. Certain herbs may be used as antibiotic alternatives and do not cause resistance in bacteria. Natural antibiotics are an important component of the innate defences of all species of life. This article reviews various natural peptide antibiotics and their importance. Natural antibiotics are a valuable intervention for fighting such infections as well as preventing the occurrence in the first place. With respect to the cure rate, 4.5% Of study participants given azithromycin has positive cultures vs. 21.1% Of patients given erythromycin or tetracycline (P = .018). With respect to side effects severe enough to warrant a change in medication, 7.4% Of patients receiving azithromycin reported suffering such side effects vs. 38.8% Of patients given erythromycin (P = .02). Among sexual partners, 28.6% Given tetracycline reported severe side effects vs. None of those given azithromycin (P = .03). The primary means of bacterial resistance to macrolides occurs by post-transcriptional methylation of the 23S bacterial ribosomal RNA. This acquired resistance can be either plasmid-mediated or chromosomal, i.E., Through mutation, and results in cross-resistance to macrolides, lincosamides, and streptogramins (An MLS-resistant phenotype).
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